A custom-compounded Bi-Estrogen cream that combines estradiol and estriol to help balance your hormones and provide relief from a wide range of menopausal symptoms.
A skin-applied blend of estradiol + estriol that gently restores estrogen to cool hot flashes, calm night sweats, improve vaginal comfort, and steady mood/sleep.
No. We start you on a low dose, check in on how you’re feeling, and adjust your formula and dosing. We always include progesterone to balance estrogen.
Bi-Est is a topical cream that you apply to your skin. It absorbs quickly, making it a simple and non-invasive part of your daily routine. Our medical team provides clear guidance for use.
Our dual-estrogen formula effectively tackles common menopausal symptoms, helping you feel more comfortable day and night.
Bi-Est Cream (30-Day Supply)
More affordable than ever. Prices start under $2 per tablet.
Still have questions? Send us a message.
A customized, skin-applied blend of estradiol + estriol that restores estrogen—paired with progesterone—to ease menopausal symptoms.
Hot flashes, night sweats, vaginal dryness/discomfort, brain fog, mood and sleep changes.
Same molecular structure as your body’s hormones for natural-feeling relief. (Compounded; not FDA-approved.)
Apply the prescribed amount daily to thin skin (e.g., inner forearms/upper thighs). Let dry, rotate sites, and wash hands.
So we can tailor your dose and E2:E3 ratio, ensure quality, and keep supply consistent.
Possible breast tenderness, spotting, headache, or mild skin irritation. Seek care for chest pain, severe headache, or leg swelling.
We start low, check in on how you’re feeling, then adjust dose and ratio as needed. We always include progesterone to balance estrogen.
Yes. A licensed clinician reviews your history and prescribes if appropriate.
Topical bioidentical treatments may reduce certain risks associated with oral hormone replacement therapy. Customizable dosing also allows for using the lowest effective dose to minimize risk.